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SKYTROFA®:
The Freedom of Once Weekly

SKYTROFA®: The Freedom of Once Weekly

More than 10,000 patients have been prescribed SKYTROFA1*

*Numbers are based on Ascendis Signature Access Program® (A·S·A·P) prescribing data as of May 1, 2024.1

In pediatric GHD treatment…

SKYTROFA is the ONLY GH that offers your patients:

Predictable release of unmodified somatropin over the course of one week2-5†

A preservative-free formulation2,4,5‡

Auto-Injector designed to deliver the full dose and minimize the potential for wasted medication2

Room temperature storage for up to 6 months2,4,5§

SKYTROFA demonstrated higher mean annualized height velocity (AHV) compared with a daily somatropin at week 52 in a clinical trial2,3

A treatment difference of 0.9 cm/year (95% CI: 0.2 to 1.5) at 52 weeks compared with daily somatropin (11.2 cm/year with SKYTROFA compared with 10.3 cm/year with daily somatropin)2,3II

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heiGHt TRIAL
SKYTROFA is a prodrug that releases active somatropin with the same molecular weight and amino acid sequence as endogenous GH. SOGROYA® (somapacitan-beco) is an hGH analog with a single substitution in the amino acid backbone (L101C) to which an albumin-binding moiety has been attached. NGENLA® (somatrogon) is a recombinant hGH with 3 CTPs from the beta chain of hCG attached.2-5
SKYTROFA does not contain preservatives. SOGROYA and NGENLA contain the preservatives phenol and metacresol, respectively.2,4,5
§ SKYTROFA can be stored at room temperature for up to 6 months. SKYTROFA cartridges can be stored at 36°F to 46°F (2°C to 8°C) in the outer carton to protect from light until the expiration date. SOGROYA can be stored at room temperature for a total of 3 days. NGENLA should be refrigerated.2,4,5
II In the phase 3 heiGHt trial comparing once-weekly SKYTROFA with a daily somatropin in 161 treatment-naïve children with GHD. The primary endpoint was mean AHV at week 52.2,3
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Expanded coverage

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Statement of Medical Necessity

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Patient Support Program

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