Convenient Dosing

SKYTROFA® dosing allows for individualization and titration based on clinical response1

  • SKYTROFA is a subcutaneous injection that can be administered at any time of day or night1
    • To avoid missed doses, SKYTROFA can be taken 5 to 9 days after the prior dose
    • The next dose should be resumed at the previous scheduled dosing day
    • At least 5 days should elapse between doses
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The recommended dose of SKYTROFA for treatment-naïve patients and those switching* from daily somatropin is 0.24 mg/kg of body weight, administered once weekly1

* When changing from daily somatropin therapy to once-weekly SKYTROFA, wait at least 8 hours between the final dose of daily somatropin and the first dose of once-weekly SKYTROFA.1
SKYTROFA single-use, prefilled cartridges are available in 9 dosage strengths1
Weight (kg) Cartridge(s) (mg hGH)
11.5 – 13.9 3.0
14 – 16.4 3.6
16.5 – 19.9 4.3
20 – 23.9 5.2
24 – 28.9 6.3
29 – 34.9 7.6
35 – 41.9 9.1
42 – 50.9 11.0
51 – 60.4 13.3
60.5 – 69.9 7.6 x 2
70 – 84.9 9.1 x 2
85 – 100 11.0 x 2
Weight-based dosing for recommended dose (0.24 mg/kg/week)1
Patients requiring a dose greater than the 13.3 mg cartridge may inject 2 cartridges per weekly dose. The same dose strength must be used for both doses in those patients requiring a double dose.1
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Simple calculation for individualized dosing
This dose calculation can be used for prescribing a dose other than 0.24 mg/kg/week1

Example Calculation
Choose the right dose for your patients based on their individual treatment goals and clinical response.