A Clinical Commitment
SKYTROFA® has been studied in over 300 children with GHD, including treatment‑naïve and treatment-experienced patients1‑3
SKYTROFA phase 3 program in pediatric GHD1‑4

A total of 298 of the 307 children with GHD who completed the heiGHt and fliGHt trials continued into the enliGHten open-label extension for long-term safety assessments1-4
Experience Growth
Once-weekly SKYTROFA: Demonstrated higher AHV* at week 52 in treatment-naïve children compared with a daily somatropin1,2
AHV and height changes from baseline at week 52: Once-weekly SKYTROFA versus daily somatropin1,2*
- The treatment difference in AHV with SKYTROFA compared with daily somatropin was 0.9 cm/year1,2
- 95% CI of 0.2 to 1.5 cm/year1,2
- The weekly dose of hGH was equivalent to 0.24 mg hGH/kg/week for both SKYTROFA and daily somatropin1
- The change in mean bone age from baseline to week 52 was similar with SKYTROFA and daily somatropin, and the observed mean BMI SDS remained within normal range for both groups2,5
Sustained growth was achieved with SKYTROFA in treatment-naïve patients6
Patients treated with SKYTROFA had a greater increase from baseline in height SDS† compared with patients treated with a daily somatropin2‡

Efficacy and Safety Guide
Learn more about the clinical differentiation of SKYTROFA.
Once-weekly SKYTROFA makes dosing easy for patients and their healthcare professionals
LEARN MORE ABOUT CONVENIENT DOSING